Absolute abundance calculation enhances the significance of microbiome data in antibiotic treatment studies

BackgroundThe intestinal microbiota contributes to the colonization resistance of the gut towards bacterial pathogens. Antibiotic treatment often negatively affects the microbiome composition, rendering the host more susceptible for infections. However, a correct interpretation of such a perturbatio...

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Bibliographic Details

Published in:	Frontiers in Microbiology
Main Authors:	Stefanie Wagner, Michael Weber, Lena-Sophie Paul, Angelika Grümpel-Schlüter, Jeannette Kluess, Klaus Neuhaus, Thilo M. Fuchs
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-03-01
Subjects:	antibiotic one health gut microbiome piglet flow cytometry spike-in
Online Access:	https://www.frontiersin.org/articles/10.3389/fmicb.2025.1481197/full