Estrogens Play a Critical Role in Stress-Related Gastrointestinal Dysfunction in a Spontaneous Model of Disorders of Gut–Brain Interaction

Background: Disorders of the gut–brain interaction (DGBI), such as irritable bowel syndrome and functional dyspepsia, are more prevalent in women than in men, with a ratio of 2:1. Furthermore, stressful life events have been reported as one of the triggers for symptoms in DGBI patients. Methods: Her...

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Bibliographic Details

Published in:	Cells
Main Authors:	Alison Accarie, Joran Toth, Lucas Wauters, Ricard Farré, Jan Tack, Tim Vanuytsel
Format:	Article
Language:	English
Published:	MDPI AG 2022-04-01
Subjects:	multifactorial DGBI model β-estradiol disorders of gut–brain interaction irritable bowel syndrome mast cells visceral hypersensitivity
Online Access:	https://www.mdpi.com/2073-4409/11/7/1214