Refining tacrolimus dosing through CYP3A5 pharmacogenetics in Taiwanese renal transplant recipients

Genetic polymorphisms in CYP3A5 affects tacrolimus (Tac) bioavailability; however the optimal genotype-guided starting dose remains undefined. This retrospective cohort study examined the effects of the CYP3A5 allele on Tac pharmacokinetics in 431 Taiwanese renal transplant recipients. Genotyping wa...

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Bibliographic Details

Published in:	Renal Failure
Main Authors:	Yen-Lin Chang, Tzu-Hung Hsiao, Yi-Ming Chen, Ching-Heng Lin, Yi-Ju Liao, Chiann-Yi Hsu, Yung‑Po Liaw, Cheng-Hsu Chen
Format:	Article
Language:	English
Published:	Taylor & Francis Group 2025-12-01
Subjects:	Tacrolimus CYP3A5 pharmacogenetics taiwanese population Renal transplantation
Online Access:	https://www.tandfonline.com/doi/10.1080/0886022X.2025.2523567