Metabolomic Differential Compounds Reflecting the Clinical Efficacy of Polyethylene Glycol Recombinant Human Growth Hormone in the Treatment of Childhood Growth Hormone Deficiency

Understanding metabolite profiles may aid in providing a reference for individualized treatment using PEG-rhGH. Therefore, this study aimed to evaluate the clinical efficacy of PEG-rhGH in treating GHD patients by using a metabolomic approach. Fifty-seven pediatric participants treated with PEG-rhGH...

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Bibliographic Details

Published in:	Frontiers in Pharmacology
Main Authors:	Ji Li, Weiwei Pan, Jianqin Qian, Yan Ni, Junfen Fu, Shaoqing Ni
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-04-01
Subjects:	growth hormone deficiency PEG-rhGH metabolomics clinical efficacy biomarkers
Online Access:	https://www.frontiersin.org/articles/10.3389/fphar.2022.864058/full