Silencing p75NTR prevents proNGF-induced endothelial cell death and development of acellular capillaries in rat retina

Accumulation of the nerve growth factor precursor (proNGF) and its receptor p75NTR have been associated with several neurodegenerative diseases in both brain and retina. However, whether proNGF contributes to microvascular degeneration remain unexplored. This study seeks to investigate the mechanism...

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Bibliographic Details

Published in:	Molecular Therapy: Methods & Clinical Development
Main Authors:	Ahmed Y Shanab, Barbara A Mysona, Suraporn Matragoon, Azza B El-Remessy
Format:	Article
Language:	English
Published:	Elsevier 2015-01-01
Online Access:	http://www.sciencedirect.com/science/article/pii/S2329050116300250