Single-cell and spatially resolved interactomics of tooth-associated keratinocytes in periodontitis

Abstract Periodontitis affects billions of people worldwide. To address relationships of periodontal niche cell types and microbes in periodontitis, we generated an integrated single-cell RNA sequencing (scRNAseq) atlas of human periodontium (34-sample, 105918-cell), including sulcular and junctiona...

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Bibliographic Details

Published in:	Nature Communications
Main Authors:	Quinn T. Easter, Bruno Fernandes Matuck, Germán Beldorati Stark, Catherine L. Worth, Alexander V. Predeus, Brayon Fremin, Khoa Huynh, Vaishnavi Ranganathan, Zhi Ren, Diana Pereira, Brittany T. Rupp, Theresa Weaver, Kathryn Miller, Paola Perez, Akira Hasuike, Zhaoxu Chen, Mandy Bush, Xufeng Qu, Janice Lee, Scott H. Randell, Shannon M. Wallet, Inês Sequeira, Hyun Koo, Katarzyna M. Tyc, Jinze Liu, Kang I. Ko, Sarah A. Teichmann, Kevin M. Byrd
Format:	Article
Language:	English
Published:	Nature Portfolio 2024-06-01
Online Access:	https://doi.org/10.1038/s41467-024-49037-y