Transcriptomic analysis of coxsackievirus B3 infection in induced pluripotent stem cell-derived brain-like endothelial cells

ABSTRACT Viral aseptic meningitis is a neuroinflammatory condition that occurs when viruses gain access to the central nervous system (CNS) and induce inflammation. The blood–brain barrier (BBB) is comprised of brain endothelial cells (BECs) that stringently regulate the passage of molecules, toxins...

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Bibliographic Details

Published in:	Journal of Virology
Main Authors:	Sarah F. Hathcock, Julia Mamana, Taryn E. Keyzer, Nadine Vollmuth, Mohammad-Reza Shokri, Henry D. Mauser, Robert N. Correll, Daryl W. Lam, Brandon J. Kim, Jon Sin
Format:	Article
Language:	English
Published:	American Society for Microbiology 2025-01-01
Subjects:	coxsackievirus B3 blood-brain barrier brain endothelial cells RNA sequencing induced pluripotent stem cells
Online Access:	https://journals.asm.org/doi/10.1128/jvi.01824-24