Idebenone Alleviates Neuroinflammation and Modulates Microglial Polarization in LPS-Stimulated BV2 Cells and MPTP-Induced Parkinson’s Disease Mice

Background: Idebenone is an antioxidant and a coenzyme Q10 analog that has been used to treat neurodegeneration disease. Some studies show idebenone exerts anti-inflammatory effects. However, whether idebenone can be used to reduce the neuroinflammation in Parkinson’s disease (PD) has been little st...

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Bibliographic Details

Published in:	Frontiers in Cellular Neuroscience
Main Authors:	Aijuan Yan, Zhihua Liu, Lu Song, Xijin Wang, Yu Zhang, Na Wu, Jingya Lin, Ying Liu, Zhenguo Liu
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2019-01-01
Subjects:	idebenone neuroinflammation microglial polarization Parkinson’s disease BV2 cells
Online Access:	https://www.frontiersin.org/article/10.3389/fncel.2018.00529/full