Iodine-Mediated Neutral and Selective N-Boc Deprotection
A simple, efficient, and alternative method has been developed for the N-Boc deprotection of structurally diverse protected amines. Selective removal of N-Boc groups was achieved with excellent yields under a solvent-free condition or in a solvent using iodine as a catalyst. The methodology involvin...
| Published in: | Journal of Chemistry |
|---|---|
| Main Authors: | , , , |
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2013-01-01
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| Online Access: | http://dx.doi.org/10.1155/2013/916960 |