Synthesis of Novel Bioactive Lipophilic Hydroxyalkyl Esters and Diesters Based on Hydroxyphenylacetic Acids

Novel lipophilic hydroxyalkyl esters were synthetized by Fischer esterification in good to excellent yields (60–96%) from a panel of hydroxyphenylacetic acids and increasing chain length (2 to 8 carbon atoms) α,ω-diols. The in vitro antioxidant activity of these compounds was evaluated by DPPH and A...

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Bibliographic Details

Published in:	Molecules
Main Authors:	Andrea Fochetti, Noemi Villanova, Andrea Lombardi, Veronica Lelli, Yuri Gazzilli, Anna Maria Timperio, Giancarlo Fabrizi, Roberta Bernini
Format:	Article
Language:	English
Published:	MDPI AG 2025-07-01
Subjects:	hydroxyphenylacetic acids hydroxyalkyl esters butyl diarylacetates lipophilicity antioxidant activity DPPH assay
Online Access:	https://www.mdpi.com/1420-3049/30/15/3087