The functional repertoire of AmpR in the AmpC β-lactamase high expression and decreasing β-lactam and aminoglycosides resistance in ESBL Citrobacter freundii

Citrobacter freundii is characterized by AmpC β-lactamases that develop resistance to β-lactam antibiotics. The production of extended-spectrum β-lactamase (ESBL) is substantially high in Escherichia coli, C. freundii, Enterobacter cloacae, and Serratia marcescens, but infrequently explored in C. fr...

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Bibliographic Details

Published in:	Heliyon
Main Authors:	Falak Naz Tariq, Mehreen Shafiq, Nadeem Khawar, Gul Habib, Haji Gul, Azam Hayat, Mujaddad Ur Rehman, Ihab Mohamed Moussa, Eman A. Mahmoud, Hosam O. Elansary
Format:	Article
Language:	English
Published:	Elsevier 2023-09-01
Subjects:	C. freundii β-lactamases AmpR mutation AmpC Oxidative stress Aminoglycosides resistance
Online Access:	http://www.sciencedirect.com/science/article/pii/S240584402306694X