A preliminary study of the miRNA restitution effect on CNV-induced miRNA downregulation in CAKUT

Abstract Background The majority of CAKUT-associated CNVs overlap at least one miRNA gene, thus affecting the cellular levels of the corresponding miRNA. We aimed to investigate the potency of restitution of CNV-affected miRNA levels to remediate the dysregulated expression of target genes involved...

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Bibliographic Details

Published in:	BMC Genomics
Main Authors:	Kristina Mitrovic, Ivan Zivotic, Ivana Kolic, Jelena Zakula, Maja Zivkovic, Aleksandra Stankovic, Ivan Jovanovic
Format:	Article
Language:	English
Published:	BMC 2024-02-01
Subjects:	CAKUT miRNA CNV miRNA mimic
Online Access:	https://doi.org/10.1186/s12864-024-10121-8