ALDH1A1 Genetic Variations May Modulate Risk of Parkinson’s Disease in Han Chinese Population

Background: Studies in animal models have suggested that aldehyde dehydrogenase 1 (encoded by ALDH1A1) protects against Parkinson’s disease (PD) by reducing toxic metabolites of dopamine. Herein we aimed to investigate whether ALDH1A1 was genetically associated with PD susceptibility in humans.Metho...

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Bibliographic Details

Published in:	Frontiers in Neuroscience
Main Authors:	Hui-Hui Fan, Qing Guo, Jing Zheng, Yi-Zhi Lian, Shi-Shi Huang, Yue Sun, Ming Zou, Jian-Hong Zhu, Xiong Zhang
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2021-03-01
Subjects:	ALDH1A1 Parkinson’s disease single nucleotide polymorphism rs7043217 genetic association
Online Access:	https://www.frontiersin.org/articles/10.3389/fnins.2021.620929/full