HFE gene variants, iron, and lipids: a novel connection in Alzheimer’s disease

Iron accumulation and associated oxidative stress in the brain have been consistently found in several neurodegenerative diseases. Multiple genetic studies have been undertaken to try to identify a cause of neurodegenerative diseases but direct connections have been rare. In the iron field, varian...

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Bibliographic Details

Published in:	Frontiers in Pharmacology
Main Authors:	Fatima eAli-Rahmani, Cara-Lynne eSchengrund, James eConnor
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2014-07-01
Subjects:	Alzheimer Disease Brain Cholesterol Iron Sphingolipids HFE
Online Access:	http://journal.frontiersin.org/Journal/10.3389/fphar.2014.00165/full