Structures of the human Wilson disease copper transporter ATP7B

Summary: The P-type ATPase ATP7B exports cytosolic copper and plays an essential role in the regulation of cellular copper homeostasis. Mutants of ATP7B cause Wilson disease (WD), an autosomal recessive disorder of copper metabolism. Here, we present cryoelectron microscopy (cryo-EM) structures of h...

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Bibliographic Details
Published in:Cell Reports
Main Authors: Guo-Min Yang, Lingyi Xu, Rou-Min Wang, Xin Tao, Zi-Wei Zheng, Shenghai Chang, Demin Ma, Cheng Zhao, Yi Dong, Shan Wu, Jiangtao Guo, Zhi-Ying Wu
Format: Article
Language:English
Published: Elsevier 2023-05-01
Subjects:
CP: Molecular biology
Online Access:http://www.sciencedirect.com/science/article/pii/S221112472300428X

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http://www.sciencedirect.com/science/article/pii/S221112472300428X

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