Cdk5 activation promotes Cos-7 cells transition towards neuronal-like cells

Cyclin-dependent kinase 5 (Cdk5) activity is specifically active in neurogenesis, and Cdk5 and neocortical neurons migration related biomarker are expressed in Cos-7 cells. However, the function of Cdk5 on the transformation of immortalized Cos-7 cells into neuronal-like cells is not clear.

Bibliographic Details

Published in:	Translational Neuroscience
Main Authors:	Bao Li, Lan Xiao-Mei, Zhang Guo-Qing, Bao Xi, Li Bo, Ma Dan-Na, Luo Hong-Yan, Cao Shi-Lu, Liu Shun-Yao, Jing E, Zhang Jian-Zhong, Zheng Ya-Li
Format:	Article
Language:	English
Published:	De Gruyter 2023-10-01
Subjects:	p35 cdk5 kinase activity neuron transformation ngf
Online Access:	https://doi.org/10.1515/tnsci-2022-0318