Adenylosuccinic Acid Is a Non-Toxic Small Molecule In Vitro and In Vivo

Adenylosuccinic acid (ASA) is a small molecule dicarboxylate that could be a strong clinical development candidate for inherited myopathies involving dysregulated purine nucleotide metabolism. Currently, there are no published pharmacokinetic/dynamic or toxicology data available, although 10-year cl...

Full description

Bibliographic Details

Published in:	Pharmaceuticals
Main Authors:	Cara A. Timpani, Lorna Rasmussen, Emma Rybalka
Format:	Article
Language:	English
Published:	MDPI AG 2023-10-01
Subjects:	adenylosuccinic acid Duchenne muscular dystrophy myopathy metabolic disease skeletal muscle toxicology
Online Access:	https://www.mdpi.com/1424-8247/16/10/1458