Cornin protects against cerebral ischemia/reperfusion injury by preventing autophagy via the PI3K/Akt/mTOR pathway

Abstract Background Ischemia stroke is the leading cause of disability, which is a consequence of vascular occlusion. The purpose of this study is to investigate the effect of cornin which is isolated from the fruit of Verbena officinalis L, against astrocytes autophagy induced by cerebral ischemia/...

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Bibliographic Details

Published in:	BMC Pharmacology and Toxicology
Main Authors:	Tianchi Lan, Yangyang Xu, Shucui Li, Ning Li, Shuping Zhang, Haibo Zhu
Format:	Article
Language:	English
Published:	BMC 2022-10-01
Subjects:	Cornin Autophagy Oxygen glucose deprivation/reperfusion Cerebral ischemia–reperfusion
Online Access:	https://doi.org/10.1186/s40360-022-00620-3