The WNT/ROR Pathway in Cancer: From Signaling to Therapeutic Intervention

The WNT pathway is one of the major signaling cascades frequently deregulated in human cancer. While research had initially focused on signal transduction centered on β-catenin as a key effector activating a pro-tumorigenic transcriptional response, nowadays it is known that WNT ligands can also ind...

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Bibliographic Details

Published in:	Cells
Main Authors:	Kerstin Menck, Saskia Heinrichs, Cornelia Baden, Annalen Bleckmann
Format:	Article
Language:	English
Published:	MDPI AG 2021-01-01
Subjects:	ROR1 ROR2 cancer WNT signaling non-canonical targeted therapy
Online Access:	https://www.mdpi.com/2073-4409/10/1/142