Loading of Extracellular Vesicles with Nucleic Acids via Hybridization with Non‐Lamellar Liquid Crystalline Lipid Nanoparticles

Abstract The translation of cell‐derived extracellular vesicles (EVs) into biogenic gene delivery systems is limited by relatively inefficient loading strategies. In this work, the loading of various nucleic acids into small EVs via their spontaneous hybridization with preloaded non‐lamellar liquid...

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Bibliographic Details

Published in:	Advanced Science
Main Authors:	Johannes Bader, Pascal Rüedi, Valeria Mantella, Silvana Geisshüsler, Finn Brigger, Bilal Muhammad Qureshi, Jaime Ortega Arroyo, Elita Montanari, Jean‐Christophe Leroux
Format:	Article
Language:	English
Published:	Wiley 2025-02-01
Subjects:	extracellular vesicles gene delivery lipid nanoparticles lipid phase transition lyotropic liquid crystal
Online Access:	https://doi.org/10.1002/advs.202404860