Rational strain design with minimal phenotype perturbation
Abstract Devising genetic interventions for desired cellular phenotypes remains challenging regarding time and resources. Kinetic models can accelerate this task by simulating metabolic responses to genetic perturbations. However, exhaustive design evaluations with kinetic models are computationally...
| الحاوية / القاعدة: | Nature Communications |
|---|---|
| المؤلفون الرئيسيون: | , , , , |
| التنسيق: | مقال |
| اللغة: | الإنجليزية |
| منشور في: |
Nature Portfolio
2024-01-01
|
| الوصول للمادة أونلاين: | https://doi.org/10.1038/s41467-024-44831-0 |