In Vitro Veritas: From 2D Cultures to Organ-on-a-Chip Models to Study Immunogenic Cell Death in the Tumor Microenvironment

Immunogenic cell death (ICD) is a functionally unique form of cell death that promotes a T-cell-dependent anti-tumor immune response specific to antigens originating from dying cancer cells. Many anticancer agents and strategies induce ICD, but despite their robust effects in vitro and in vivo on mi...

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Bibliographic Details

Published in:	Cells
Main Authors:	Dmitri V. Krysko, Robin Demuynck, Iuliia Efimova, Faye Naessens, Olga Krysko, Elena Catanzaro
Format:	Article
Language:	English
Published:	MDPI AG 2022-11-01
Subjects:	immunogenic cell death tumor microenvironment 3D cell culture spheroids organoids bioperfusion bioreactors
Online Access:	https://www.mdpi.com/2073-4409/11/22/3705