A Novel Peptide for Simultaneously Enhanced Treatment of Head and Neck Cancer and Mitigation of Oral Mucositis.

We have characterized a novel 21 amino acid-peptide derived from Antrum Mucosal Protein (AMP)-18 that mediates growth promotion of cultured normal epithelial cells and mitigates radiation-induced oral mucositis in animal models, while suppressing in vitro function of cancer cells. The objective of t...

Full description

Bibliographic Details
Published in:PLoS ONE
Main Authors: Peili Chen, Maria Mancini, Stephen T Sonis, Juan Fernandez-Martinez, Jing Liu, Ezra E W Cohen, F Gary Toback
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Online Access:http://europepmc.org/articles/PMC4822960?pdf=render