The Transcription Factor T-Bet Is Required for Optimal Type I Follicular Helper T Cell Maintenance During Acute Viral Infection

Follicular helper T cells (TFH cells), known as the primary “helpers” of the germinal center (GC) reaction, promote the humoral immune response to defend against various pathogens. Under conditions of infection by different types of pathogens, many shared transcription factors (TFs), such as Bcl-6,...

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發表在:	Frontiers in Immunology
Main Authors:	Pengcheng Wang, Youping Wang, Luoyingzi Xie, Minglu Xiao, Jialin Wu, Lifan Xu, Qiang Bai, Yaxing Hao, Qizhao Huang, Xiangyu Chen, Ran He, Baohua Li, Sen Yang, Yaokai Chen, Yuzhang Wu, Lilin Ye
格式:	Article
語言:	英语
出版:	Frontiers Media S.A. 2019-03-01
主題:	T-bet follicular helper T cells type I immune response humoral response T cell differentiation transcriptional regulation
在線閱讀:	https://www.frontiersin.org/article/10.3389/fimmu.2019.00606/full