Mitigation of motion effects in pencil-beam scanning – Impact of repainting on 4D robustly optimized proton treatment plans for hepatocellular carcinoma

Proton fields delivered by the active scanning technique can be interfered with the intrafractional motion. This in-silico study seeks to mitigate the dosimetric impacts of motion artifacts, especially its interplay with the time-modulated dose delivery. Here four-dimensional (4d) robust optimizatio...

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Bibliographic Details

Published in:	Zeitschrift für Medizinische Physik
Main Authors:	Hilda Siregar, Christian Bäumer, Oliver Blanck, Mark Chan, Erik Engwall, Sandija Plaude, Bernhard Spaan, Beate Timmermann, Jörg Wulff
Format:	Article
Language:	English
Published:	Elsevier 2022-02-01
Subjects:	Proton therapy Pencil-beam scanning Motion management Interplay effect Repainting Robust optimization
Online Access:	http://www.sciencedirect.com/science/article/pii/S093938892030091X