TGF-β-activated circRYK drives glioblastoma progression by increasing VLDLR mRNA expression and stability in a ceRNA- and RBP-dependent manner

Abstract Background The TGF-β signalling pathway is intricately associated with the progression of glioblastoma (GBM). The objective of this study was to examine the role of circRNAs in the TGF-β signalling pathway. Methods In our research, we used transcriptome analysis to search for circRNAs that...

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Bibliographic Details
Published in:Journal of Experimental & Clinical Cancer Research
Main Authors: Yuhang Wang, Binbin Wang, Wenping Cao, Xiupeng Xu
Format: Article
Language:English
Published: BMC 2024-03-01
Subjects:
Online Access:https://doi.org/10.1186/s13046-024-03000-3