Formation and optimization of three-dimensional organoids generated from urine-derived stem cells for renal function in vitro

Abstract Background Organoids play an important role in basic research, drug screening, and regenerative medicine. Here, we aimed to develop a novel kind of three-dimensional (3D) organoids generated from urine-derived stem cells (USCs) and to explore whether kidney-specific extracellular matrix (kE...

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Bibliographic Details

Published in:	Stem Cell Research & Therapy
Main Authors:	Guoliang Sun, Beichen Ding, Meimei Wan, Liang Chen, John Jackson, Anthony Atala
Format:	Article
Language:	English
Published:	BMC 2020-07-01
Subjects:	Urine-derived stem cells Organoids Extracellular matrix Drug screening Renal function
Online Access:	http://link.springer.com/article/10.1186/s13287-020-01822-4