Canonical Wnt/β-catenin signalling is essential for optic cup formation.
A multitude of signalling pathways are involved in the process of forming an eye. Here we demonstrate that β-catenin is essential for eye development as inactivation of β-catenin prior to cellular specification in the optic vesicle caused anophthalmia in mice. By achieving this early and tissue-spec...
| Published in: | PLoS ONE |
|---|---|
| Main Authors: | , , |
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2013-01-01
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24324671/?tool=EBI |