ac4C acetylation regulates mRNA stability and translation efficiency in osteosarcoma

Objective: N4-acetylcytidine (ac4C) acetylation can promote target gene expression through improved mRNA stability. To explore the role of ac4C acetylation in osteosarcoma, U2OS and MG63 cell lines were treated with the N-acetyltransferase 10 (NAT10) inhibitor Remodelin. Reverse transcription–polyme...

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Bibliographic Details

Published in:	Heliyon
Main Authors:	Wenjie Zhang, Jia Gao, Lei Fan, Juan Wang, Bin He, Yunhua Wang, Xiaotong Zhang, Hui Mao
Format:	Article
Language:	English
Published:	Elsevier 2023-06-01
Subjects:	ac4C acetylation NAT10 Osteosarcoma acRIP-seq FNTB gene
Online Access:	http://www.sciencedirect.com/science/article/pii/S2405844023043116