Co-dependent Assembly of Drosophila piRNA Precursor Complexes and piRNA Cluster Heterochromatin

Summary: In Drosophila, the piRNAs that guide germline transposon silencing are produced from heterochromatic clusters marked by the HP1 homolog Rhino. We show that Rhino promotes cluster transcript association with UAP56 and the THO complex, forming RNA-protein assemblies that are unique to piRNA p...

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Bibliographic Details

Published in:	Cell Reports
Main Authors:	Gen Zhang, Shikui Tu, Tianxiong Yu, Xiao-Ou Zhang, Swapnil S. Parhad, Zhiping Weng, William E. Theurkauf
Format:	Article
Language:	English
Published:	Elsevier 2018-09-01
Online Access:	http://www.sciencedirect.com/science/article/pii/S2211124718313858