The GPIb-IX complex on platelets: insight into its novel physiological functions affecting immune surveillance, hepatic thrombopoietin generation, platelet clearance and its relevance for cancer development and metastasis
Abstract The glycoprotein (GP) Ib-IX complex is a platelet receptor that mediates the initial interaction with subendothelial von Willebrand factor (VWF) causing platelet arrest at sites of vascular injury even under conditions of high shear. GPIb-IX dysfunction or deficiency is the reason for the r...
| 發表在: | Experimental Hematology & Oncology |
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| Main Authors: | , |
| 格式: | Article |
| 語言: | 英语 |
| 出版: |
BMC
2022-04-01
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| 主題: | |
| 在線閱讀: | https://doi.org/10.1186/s40164-022-00273-2 |