How to maintain the maximal level of blinding in randomisation for a placebo-controlled drug trial

We illustrate the approach of randomising treatments and compare it with the traditional approach of randomising patients, using a case study drawn from the authors’ experience in clinical trials. The setting is a double-blind parallel two-arm randomised controlled trial (RCT), but the method in thi...

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Bibliographic Details
Published in:Contemporary Clinical Trials Communications
Main Authors: Lei Clifton, David A. Clifton
Format: Article
Language:English
Published: Elsevier 2019-06-01
Online Access:http://www.sciencedirect.com/science/article/pii/S2451865419300158