Enhanced alloresponse to platelet transfusion due to immune dysregulation following ablative chemotherapy in mice

IntroductionAlloimmunization is common following platelet transfusion and can result in negative outcomes for recipients such as refractoriness to subsequent transfusions and rejection of transplants. Healthy people do not receive blood transfusions, and the diseases and therapies that result in a n...

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Bibliographic Details

Published in:	Frontiers in Immunology
Main Authors:	Rachael P. Jackman, Orsolya Darst, Betty Gaillard, Johnson Q. Tran, Mary M. Tomayko, Marcus O. Muench
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-11-01
Subjects:	platelets alloimmunization chemotherapy recipient health alloantibodies transitional B cells
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2023.1281123/full