Btg2 Promotes Focal Segmental Glomerulosclerosis via Smad3‐Dependent Podocyte‐Mesenchymal Transition

Abstract Podocyte injury plays a critical role in the progression of focal segmental glomerulosclerosis (FSGS). Here, it is reported that B‐cell translocation gene 2 (Btg2) promotes Adriamycin (ADR)‐induced FSGS via Smad3‐dependent podocyte‐mesenchymal transition. It is found that in FSGS patients a...

Full description

Bibliographic Details

Published in:	Advanced Science
Main Authors:	Qiong‐ Dan Hu, Hong‐Lian Wang, Jian Liu, Tao He, Rui‐Zhi Tan, Qiong Zhang, Hong‐Wei Su, Fahsai Kantawong, Hui‐Yao Lan, Li Wang
Format:	Article
Language:	English
Published:	Wiley 2023-11-01
Subjects:	Btg2 epithelial‐mesenchymal transition focal segmental glomerulosclerosis podocyte TGF‐β/Smad3 signaling
Online Access:	https://doi.org/10.1002/advs.202304360