Clusterin mediates hydroquinone-induced cytotoxic responses in HL-60 differentiated cells

Abstract Benzene is a crucial industrial hydrocarbon, posing significant health risks due to its toxic metabolites like hydroquinone (HQ). This study investigates the role of clusterin (CLU) in benzene toxicity by analyzing its protein and mRNA levels, as well as the expression of Bcl-2 and Bax, to...

Full description

Bibliographic Details
Published in:Scientific Reports
Main Authors: Peimao Li, Qirui Gong, Dianpeng Wang, Zhimin Zhang, Wen Zhang
Format: Article
Language:English
Published: Nature Portfolio 2024-12-01
Subjects:
Benzene toxicity
Clusterin
Hydroquinone
Biomarker
Apoptosis
Online Access:https://doi.org/10.1038/s41598-024-82140-0

Internet

https://doi.org/10.1038/s41598-024-82140-0

Similar Items