Placebo response and effect in randomized clinical trials: meta-research with focus on contextual effects

Abstract Background Contextual effects (i.e., placebo response) refer to all health changes resulting from administering an apparently inactive treatment. In a randomized clinical trial (RCT), the overall treatment effect (i.e., the post-treatment effect in the intervention group) can be regarded as...

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Bibliographic Details

Published in:	Trials
Main Authors:	Sigurlaug H. Hafliðadóttir, Carsten B. Juhl, Sabrina M. Nielsen, Marius Henriksen, Ian A. Harris, Henning Bliddal, Robin Christensen
Format:	Article
Language:	English
Published:	BMC 2021-07-01
Subjects:	Placebo response Placebo effect Contextual effects Proportional contextual effect
Online Access:	https://doi.org/10.1186/s13063-021-05454-8