Multi-omics reveals lactylation-driven regulatory mechanisms promoting tumor progression in oral squamous cell carcinoma

Abstract Background Lactylation, a post-translational modification, is increasingly recognized for its role in cancer progression. This study investigates its prevalence and impact in oral squamous cell carcinoma (OSCC). Results Immunohistochemical staining of 81 OSCC cases shows lactylation levels...

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Bibliographic Details
Published in:Genome Biology
Main Authors: Fengyang Jing, Lijing Zhu, Jianyun Zhang, Xuan Zhou, Jiaying Bai, Xuefen Li, Heyu Zhang, Tiejun Li
Format: Article
Language:English
Published: BMC 2024-10-01
Subjects:
Oral squamous cell carcinoma
Lactylation
Multi-omics analysis
Oncogenes
Online Access:https://doi.org/10.1186/s13059-024-03383-8

Internet

https://doi.org/10.1186/s13059-024-03383-8

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