Validated Stability Indicating and Assay Method Development of Linagliptin in Formulation by RP-HPLC Using Quality by Design

Quality by Design (QbD) approach was used to facilitate stability indicating HPLC method development of linagliptin (LIN) in tablet dosage form. The method was developed using the PrimesilC18, 250 mm x 4.6 mm, 5µ column using the mobile phase consisting of 0.3% TEA: methanol. (60:40 v/v) pH 4.5 adju...

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Bibliographic Details

Published in:	Orbital: The Electronic Journal of Chemistry
Main Authors:	Anvesha V. Ganorkar, Sonali S. Askarkar, Krishna R. Gupta, Milind J. Umekar
Format:	Article
Language:	English
Published:	Universidade Federal de Mato Grosso do Sul 2020-06-01
Subjects:	assay Box-Behnken design linagliptin stability indicating validation
Online Access:	https://periodicos.ufms.br/index.php/orbital/article/view/15745