Host-directed therapeutic targets in macrophages and their ligands against mycobacteria tuberculosis

ABSTRACT Although current combination regimens of antibiotics have significantly improved tuberculosis (TB) cure rates, substantial challenges persist in the global effort to end TB. These include poor patient compliance, the emergence of drug-resistant strains due to prolonged treatments, and the p...

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Bibliographic Details

Published in:	Infection and Immunity
Main Authors:	Jin Li, Yanmei Wang, Lei He, Luchuan Yang, Tao Tao, Lang Bai, Youfu Luo
Format:	Article
Language:	English
Published:	American Society for Microbiology 2025-10-01
Subjects:	host-directed therapies drug resistance macrophage polarization metabolism reprogramming Mycobacterium tuberculosis
Online Access:	https://journals.asm.org/doi/10.1128/iai.00063-25