The Use of a Non-Conventional Long-Lived Gallium Radioisotope ⁶⁶Ga Improves Imaging Contrast of EGFR Expression in Malignant Tumours Using DFO-ZEGFR:2377 Affibody Molecule

Epidermal growth factor receptor (EGFR) is overexpressed in many malignancies. EGFR-targeted therapy extends survival of patients with disseminated cancers. Radionuclide molecular imaging of EGFR expression would make EGFR-directed treatment more personalized and therefore more efficient. A previous...

Full description

Bibliographic Details

Published in:	Pharmaceutics
Main Authors:	Maryam Oroujeni, Tianqi Xu, Katherine Gagnon, Sara S. Rinne, Jan Weis, Javad Garousi, Ken G. Andersson, John Löfblom, Anna Orlova, Vladimir Tolmachev
Format:	Article
Language:	English
Published:	MDPI AG 2021-02-01
Subjects:	epidermal growth factor receptor affibody molecule PET imaging gallium-66 ZEGFR:2377 A431 xenograft
Online Access:	https://www.mdpi.com/1999-4923/13/2/292