Safety and Efficacy of Combined Injection of Pure-μ-Opioid Agonist with Tramadol as an Opioid Induction Agent for Opioid-Naïve Cancer Patients

Background: Tramadol is known to provide synergistic analgesia when used in combination with morphine. Objectives: The aims of this study were: (1) to introduce an opioid combination therapy using pure-μ-opioid receptor agonist (OPI) + tramadol injections (OPI + tramadol) and (2) to elucidate safety...

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Bibliographic Details

Published in:	Palliative Medicine Reports
Main Authors:	Tetsumi Sato, Shigeki Ono, Tetsu Sato, Rei Tanaka, Yoshiko Kamo, Tomomi Suzuki
Format:	Article
Language:	English
Published:	Mary Ann Liebert 2024-10-01
Subjects:	cancer pain μ-opioid receptor agonist opioid combination therapy opioid naïve tramadol
Online Access:	https://www.liebertpub.com/doi/10.1089/pmr.2023.0061