SMYD2 glutathionylation contributes to degradation of sarcomeric proteins

Ischemic reperfusion or nutrient deprivation that produces reactive oxygen species can lead to a loss of muscle contractile function. Here the authors show that glutathionylation of the lysine methyltransferase SMYD2 contributes to degradation or disassembly of sarcomeres.

書目詳細資料

發表在:	Nature Communications
Main Authors:	Dhanushka N. P. Munkanatta Godage, Garrett C. VanHecke, Kusal T. G. Samarasinghe, Han-Zhong Feng, Mark Hiske, Joshua Holcomb, Zhe Yang, Jian-Ping Jin, Charles S. Chung, Young-Hoon Ahn
格式:	Article
語言:	英语
出版:	Nature Portfolio 2018-10-01
在線閱讀:	https://doi.org/10.1038/s41467-018-06786-x