Novel platform for engineering stable and effective vaccines against botulinum neurotoxins A, B and E

Botulinum neurotoxin (BoNT), produced by Clostridium botulinum, is the most toxic protein known, capable of causing severe paralysis and posing a significant bioterrorism threat due to its extreme lethality even in minute quantities. Despite this, there are currently no FDA-approved vaccines for wid...

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Bibliographic Details

Published in:	Frontiers in Immunology
Main Authors:	Yang Liu, Xiaoyu Liu, Weiwei Chen, Yunzhou Yu, Jianghui Meng, Jiafu Wang
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2024-09-01
Subjects:	vaccine botulinum neurotoxin streptavidin botulism therapeutics protein engineering
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2024.1469919/full