p53-dependent chromatin relaxation is required for DNA double-strand break repair

The tumor suppressor p53, an indispensable nuclear transcription factor, plays a central role in orchestrating cellular responses when DNA damage occurs. In this study, we demonstrate that in the initial phases of DNA double-strand break (DSB) repair, p53 is rapidly recruited to sites of damage and...

詳細記述

書誌詳細

出版年:	Acta Biochimica et Biophysica Sinica
主要な著者:	Chen Hongyu, Shan Jin, Qi Wenjing, Chen Lili, Zeng Xianlu
フォーマット:	論文
言語:	英語
出版事項:	China Science Publishing & Media Ltd. 2025-02-01
主題:	DNA damage repair DNA double-strand breaks (DSBs) p53 chromatin relaxation
オンライン･アクセス:	https://www.sciengine.com/doi/10.3724/abbs.2025008