Whole transcriptome sequencing reveals a TCF4-ZNF384 fusion in acute lymphoblastic leukemia

Previous studies have shown that, the clinical features and prognosis of ZNF384-rearranged pediatric acute lymphoblastic leukemia (ALL) depend on its translocation partners. We report two cases of TCF4-ZNF384 fusion, one 6-year-old girl and one 10-year-old boy, both diagnosed by whole-transcriptome...

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Bibliographic Details

Published in:	Frontiers in Oncology
Main Authors:	Zhengyu Wu, Fang Zhang, Chengzhu Liu, Shuhong Shen, Jinhua Chu, Linhai Yang, Zhiwei Xie, Yu Liu, Kangkang Liu, Ningling Wang
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-08-01
Subjects:	acute lymphoblastic leukemia ZNF384 RNA sequencing TCF4 pediatic
Online Access:	https://www.frontiersin.org/articles/10.3389/fonc.2022.900054/full