Efficient synthesis and antioxidant activity of novel N-propargyl tetrahydroquinoline derivatives through the cationic Povarov reaction

New N-propargyl tetrahydroquinolines 6a-g have been synthesized efficiently through the cationic Povarov reaction (a domino Mannich/Friedel-Crafts reaction), catalyzed by Indium (III) chloride (InCl3), from the corresponding N-propargylanilines preformed, formaldehyde and N-vinylformamide, with good...

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Bibliographic Details

Published in:	Heliyon
Main Authors:	Yeray A. Rodriguez Núñez, Maximiliano Norambuena, Arnold R. Romero Bohorquez, Alejandro Morales-Bayuelo, Margarita Gutíerrez
Format:	Article
Language:	English
Published:	Elsevier 2019-08-01
Subjects:	Organic chemistry Theoretical chemistry Pharmaceutical chemistry Tetrahydroquinolines Propragylamines Antioxidant activity
Online Access:	http://www.sciencedirect.com/science/article/pii/S2405844019358347