Automated quantification of photoreceptor outer segments in developing and degenerating retinas on microscopy images across scales

The functionality of photoreceptors, rods, and cones is highly dependent on their outer segments (POS), a cellular compartment containing highly organized membranous structures that generate biochemical signals from incident light. While POS formation and degeneration are qualitatively assessed on m...

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Bibliographic Details

Published in:	Frontiers in Molecular Neuroscience
Main Authors:	Suse Seidemann, Florian Salomon, Karl B. Hoffmann, Thomas Kurth, Ivo F. Sbalzarini, Robert Haase, Marius Ader
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2024-05-01
Subjects:	photoreceptor outer segment cone retinal development retinal degeneration supervised machine learning segmentation
Online Access:	https://www.frontiersin.org/articles/10.3389/fnmol.2024.1398447/full