Inhibition of VEGFR-3 by SAR131675 decreases renal inflammation and lymphangiogenesis in the murine lupus nephritis model

Abstract Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterized by immune-complex deposits and inflammatory cell infiltrations in multiple organs. Approximately half of lupus patients have nephritis. Lymphangiogenesis is the proliferation of lymphatic vessels (LVs), which r...

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出版年:	Cell Death Discovery
主要な著者:	Tian Wang, Wenjia Li, Ji-Hyun Yeom, Zhiheng Liu, Kyoung Min Kim, Kyung Pyo Kang
フォーマット:	論文
言語:	英語
出版事項:	Nature Publishing Group 2025-07-01
オンライン･アクセス:	https://doi.org/10.1038/s41420-025-02624-4