Case Report: Autoimmune Lymphoproliferative Syndrome vs. Chronic Active Epstein-Barr Virus Infection in Children: A Diagnostic Challenge

Autoimmune lymphoproliferative syndrome (ALPS) is a disorder characterized by a disruption of the lymphocyte apoptosis pathway, self-tolerance, and immune system homeostasis. Defects in genes within the first apoptosis signal (FAS)-mediated pathway cause an expansion of autoreactive double-negative...

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Bibliographic Details

Published in:	Frontiers in Pediatrics
Main Authors:	Aleksandra Szczawińska-Popłonyk, Elzbieta Grześk, Eyal Schwartzmann, Anna Materna-Kiryluk, Jadwiga Małdyk
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2021-12-01
Subjects:	autoimmune lymphoproliferative syndrome chronic active Epstein-Barr virus infection lymphoproliferation children immunodeficiency–primary
Online Access:	https://www.frontiersin.org/articles/10.3389/fped.2021.798959/full