Molecular Dynamics Simulations Reveal Canonical Conformations in Different pMHC/TCR Interactions

The major defense system against microbial pathogens in vertebrates is the adaptive immune response and represents an effective mechanism in cancer surveillance. T cells represent an essential component of this complex system. They can recognize myriads of antigens as short peptides (p) originated f...

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Bibliographic Details

Published in:	Cells
Main Authors:	Josephine Alba, Lorenzo Di Rienzo, Edoardo Milanetti, Oreste Acuto, Marco D’Abramo
Format:	Article
Language:	English
Published:	MDPI AG 2020-04-01
Subjects:	molecular dynamics biophysics protein-membrane T cell antigen receptor
Online Access:	https://www.mdpi.com/2073-4409/9/4/942